The Outlast Trials Pharmacist
Screenshot by The Guide Hall

The Outlast Trials: All Prescriptions and Which to Unlock First

When you’re not sprinting through the hallways of a dilapidated police predict in a desperate bid for your life, you’ll wind up wandering the hallways of the Sleep Room. Here, you’ll find a handful of NPCs, like The Pharmacist, where you can spend Murkoff Dollars to unlock persistent upgrades called Prescriptions in The Outlast Trials!

All Prescriptions in The Outlast Trials

To unlock Prescriptions in The Outlast Trials, you must reach level 3 and speak with The Pharmacist. She’s waiting for you just outside the doors after receiving your grade for completing any Trial. She’ll sell you upgrades in the form of Prescriptions, with some teaching you how to slide in the game, others offering healing, and so much more.

Tier 1

PrescriptionDescription
Instant UseHold down the interact button to use an item instantly instead of picking it up.
SlidePress crouch while running to perform a slide.
RegenerationYour health regenerates for a single bracket after a brief delay.
Self Defense TechniqueUse a bottle or brick from your inventory to escape a Pouncer’s grapple.
Hard KickHelp your teammates from a grapple without exhausting yourself.
Stay of ExecutionSaving a teammate from execution will no longer exhaust you.
Run and Smash DoorsInstantly open doors while running, but locked doors become cracked.

Tier 2

PrescriptionDescription
Expanded InventoryExpand your inventory by a single slot.
Doors BashedBreak through a locked door in two hits.
Breaching TechniqueBashing no longer depletes your stamina.
Speed BoostIncreases your overall running speed.
EnduranceReduced stamina consumption while running.
AthleteImcreases max stamina.
GymnastReduces stamina consumption while jumping and climbing.
Battery ExtensionYour night vision battery life is extended.
Heavy TrainingIncreases movement speed while carrying large objects.

Tier 3

PrescriptionDescription
Stamina RecoveryIncreases stamina regeneration.
Deep BreathsFaster overall recovery from exhaustion.
Advanced RegenerationHealth regeneration begins sooner.
RevitalizeFully restore health when revives using a syringe or respawn.
Anti-AmbushThrow a projectile at hiding spots to remove hidden enemies.
MedicHelp and revive teammates faster.
ResistanceBreak free from traps and grapples faster.
Related: Does The Outlast Trials Have Proximity Chat? – Answered

Which Prescriptions to Pick First in The Outlast Trials

You’ll only earn one or two Murkoff Dollars per Trial, so use them wisely! I recommend unlocking the following Prescriptions first:

  • Regeneration
  • Self Defense Technique
  • Run and Smash Doors
  • Expanded Inventory
  • Battery Extension
  • Athlete
  • Advanced Regeneration
  • Medic
  • Resistance

These prove helpful whether you’re playing the game solo or with teammates!


The Guide Hall spent a lot of time talking to Nurse Barlow, definitely because of the Prescriptions, not for any other reason. Come on back for more of The Outlast Trials game guides soon!